Benefits
- For chronic pain relief
- Offers a natural source of PEA from non-GMO safflower oil
- Micronized for improved bioavailability
- Provides 400 mg PEA in each capsule, allowing for easy and clinically relevant dosing
- Suitable for vegetarians and vegans
Feature Summary
Palmitoylethanolamide (PEA) is an endogenously produced lipid that mediates the resolution of neuroinflammation and clinically reduces pain from a variety of sources. PEA is a type of fatty acid ethanolamine produced in microglia and mast cells, where it downregulates the activation of both cell types; levels of PEA are increased in brain areas involved in nociception, and appear to modulate protective responses to both inflammation and pain. Its effects are mediated via direct activation of PPAR-a and GPR55 receptors, and potentially by indirect activation of CB1 and CB2 receptors and the TRPV1 channel (i.e., the capsaicin receptor).5,6
Medicinal Ingredients
| Each Capsule Contains: | |
| Palmitoylethanolamide (PEA) | 400 mg |
| PEA (palmitoylethanolamide) is a fatty-acid-like compound which is extracted from non-GMO safflower oil. Micronized for improved solubility and absorption. |
Non-Medicinal Ingredients
Vegetarian capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), silica, stearic acid.
Dosage:
Recommended Adult Dose: 1 capsule 1–3 times per day or as directed by a health care practitioner.
Allergens:
Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.