- Offers balance of key fat-soluble vitamins, A, D, and K, critical to bone health
- Contains vitamin K2 (MK-7), the most bioactive and long-lasting form
- K2 (MK-7) helps increase vertebral bone mineral density among postmenopausal women
- Provides vitamin D3 effective in maintaining blood levels of 25-OH vitamin D23
- Optimal form of vitamin A, palmitate
- Suitable for vegetarians
Vitamin K2, D3 and A provides clinically relevant doses of the three fat-soluble vitamins essential to optimal bone health. Although needed for cardiovascular health, blood sugar regulation, immune function, and inflammation control, vitamins A, D, and K2 have complementary physiological bone-related functions, such as modulating gene expression in osteoblasts and carboxylating osteocalcin, an enzyme needed for bone formation. This is exemplified by a reduction in undercarboxylated osteocalcin and an increase in bone mineral density (BMD) in postmenopausal women when vitamin K is added to vitamin D supplementation.
Vitamin D has diverse and significant functions in multiple body systems, and widespread deficiency magnifies these crucial roles. Supplementation is associated with a well-established reduction in osteoporotic fracture when taken daily at a clinically relevant dose. Correcting a vitamin D deficiency is critical when supplementing with vitamin A, as vitamin A appears to promote bone health if vitamin D levels are adequate. Additionally, maternal vitamin A levels during pregnancy have been associated with the peak bone mass and bone strength of their children, highlighting the unrecognized importance of vitamin A for lifelong bone health, in parallel to the effect of vitamin D on peak bone mass. Vitamin K is now recognized as necessary for the carboxylation of enzymes critical for both bone and blood vessel health.14-18 Indeed, meta-analysis has shown an improvement in vertebral bone mineral density (BMD) and a reduction in fracture among postmenopausal women with osteoporosis, while controlled trial data shows a reduction in the age-related decline in BMD among healthy postmenopausal women. The naturally derived MK-7 form in Vitamin K2, D3 and A has a longer half-life than any other form.
|Each Serving (4 Drops [0.25 ml]) Contains:|
|Vitamin A (Palmitate)||500 IU (151 mcg RAE)|
|Vitamin D3 (Cholecalciferol)||1000 IU (25 mcg)|
|Vitamin K2 (Menaquinone-7) (MK-7) (natto bean)||50 mcg|
Medium chain triglycerides, organic flaxseed oil, natural vitamin E (non-GMO sunflower oil), natural vanilla flavour
Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, corn, egg, fish, shellfish, salt, tree nuts, or GMOs. Suitable for vegetarians. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.
1 serving (0.25 ml) per day or as directed by a health care practitioner.